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Scientific Presentations

An Evaluation of the Ef cacy of a Low Dose, Bedtime, Sublingual Formulation of Cyclobenzaprine (TNX-102 SL) in Military-Related PTSD

An Evaluation of the Ef cacy of a Low Dose, Bedtime, Sublingual Formulation of Cyclobenzaprine (TNX-102 SL) in Military-Related PTSD

Poster Presentation at the NEI Psychopharmacology Congress in November 2015.

Gregory M. Sullivan, Judy F. Gendreau, R. Michael Gendreau, Amy Schaberg, Bruce L. Daugherty, Heather Jividen, Ashild Peters, Perry Peters, Seth Lederman

Uploaded: Nov 13, 2015
Type: Pdf
Bedtime, Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL) for the Treatment of Fibromyalgia: Results of a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study

Bedtime, Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL) for the Treatment of Fibromyalgia: Results of a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study

Poster Presentation at the American College of Rheumatology (ACR) 2015 Annual Meeting in San Francisco, CA

Lederman S, Gendreau RM, Clauw DJ, Arnold LM, Gendreau J, Daugherty B, Forst A. Bedtime, Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL) for the Treatment of Fibromyalgia: Results of a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study [abstract]. Arthritis Rheumatol. 2015; 67 (Suppl 10).

Uploaded: Nov 10, 2015
Type: Pdf
Relationship of Sleep Quality and Fibromyalgia Outcomes in a Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study of Bedtime, Rapidly Absorbed, Sublingual Cyclobenzaprine (TNX-102 SL)

Relationship of Sleep Quality and Fibromyalgia Outcomes in a Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study of Bedtime, Rapidly Absorbed, Sublingual Cyclobenzaprine (TNX-102 SL)

Poster Presentation at the American College of Rheumatology (ACR) 2015 Annual Meeting in San Francisco, CA

Moldofsky H, Gendreau RM, Clauw DJ, Gendreau J, Vaughn B, Daugherty B, Forst A, Sullivan G, Lederman S. Relationship of Sleep Quality and Fibromyalgia Outcomes in a Phase 2b Randomized, Double-Blind, Placebo-Controlled Study of Bedtime, Rapidly Absorbed, Sublingual Cyclobenzaprine (TNX-102 SL) [abstract]. Arthritis Rheumatol. 2015; 67 (Suppl 10).

Uploaded: Nov 10, 2015
Type: Pdf
Responder Compared to Mean Change Analyses in a Fibromyalgia Phase 2b Clinical Study of Bedtime Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL)

Responder Compared to Mean Change Analyses in a Fibromyalgia Phase 2b Clinical Study of Bedtime Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL)

Poster Presentation at the American College of Rheumatology (ACR) 2015 Annual Meeting in San Francisco, CA

Gendreau RM, Clauw DJ, Gendreau J, Daugherty B, Lederman S. Responder Compared to Mean Change Analyses in a Fibromyalgia Phase 2b Clinical Study of Bedtime Rapidly Absorbed Sublingual Cyclobenzaprine (TNX-102 SL) [abstract]. Arthritis Rheumatol. 2015; 67 (Suppl 10).

Uploaded: Nov 10, 2015
Type: Pdf
The AtEase Study: An Evaluation of the Efficacy of a Low Dose, Bedtime, Sublingual Formulation of Cyclobenzaprine (TNX-102 SL) for the Treatment of Military-Related PTSD

The AtEase Study: An Evaluation of the Efficacy of a Low Dose, Bedtime, Sublingual Formulation of Cyclobenzaprine (TNX-102 SL) for the Treatment of Military-Related PTSD

Poster Presentation at the Military Health System Research Symposium (MHSRS) 2015 Annual Meeting in Fort Lauderdale, FL

Sullivan GM, Gendreau JF, Gendreau RM, Schaberg A, Daugherty BL, Jividen H, Peters A, Peters P, Lederman S. The AtEase Study: An Evaluation of the Efficacy of a Low Dose, Bedtime, Sublingual Formulation of Cyclobenzaprine (TNX-102 SL) for the Treatment of Military-Related PTSD. Poster session presented at: 2015 Military Health System Research Symposium (MHSRS); 2015 Aug 17-21; Ft. Lauderdale, FL.

Uploaded: Aug 18, 2015
Type: Pdf
(R)-isometheptene* (IMH) Binds to the Imidazoline-1 Receptor and (S)-IMH increases Blood Pressure: Potentially Superior Benefit-to-Risk Ratio for (R)-IMH as an Analgesic for Headache

(R)-isometheptene* (IMH) Binds to the Imidazoline-1 Receptor and (S)-IMH increases Blood Pressure: Potentially Superior Benefit-to-Risk Ratio for (R)-IMH as an Analgesic for Headache

Poster Presentation at the American Headache Society (AHS) 2015 Annual Meeting in Washington, DC

Daugherty B, Gershell L, Lederman S. (R)-Isometheptene (IMH)* Binds to the Imidazole-1 Receptor and (S)-IMH Increases Blood Pressure: Potentially Superior Benefit to Risk Ratio for (R)-IMH as an Analgesic for Headache. Headache. 2015; 55: 172.

Uploaded: Jun 22, 2015
Type: Pdf
The (R)- isomer of isometheptene*, decreases trigeminal sensitivity in the Inflammatory Soup and Spontaneous Trigeminal Allodynia rat models

The (R)- isomer of isometheptene*, decreases trigeminal sensitivity in the Inflammatory Soup and Spontaneous Trigeminal Allodynia rat models

Poster Presentation at the American Headache Society (AHS) 2015 Annual Meeting in Washington, DC

Fried NT, Oshinsky ML, Daugherty BL, Lederman S, Elliott MB. The (R)-isomer of Isometheptene*, decreases Trigeminal Sensitivity in a Rat Model of Primary Headache. 2015; 55: 184.

Uploaded: Jun 22, 2015
Type: Pdf
TNX-102 SL* for the Treatment of Fibromyalgia: Role of Nonrestorative Sleep on Pain Centralization

TNX-102 SL* for the Treatment of Fibromyalgia: Role of Nonrestorative Sleep on Pain Centralization

Poster Presentation at the European Union League Against Rheumatism (EULAR) 2015 Annual Meeting in Rome, IT

Lederman S, Clauw D, Gendreau JF, Arnold L, Moldofsky H, Mease P, Daugherty BL, Gendreau RM. THU0325 TNX-102 SL for the Treatment of Fibromyalgia: Role of Nonrestorative Sleep on Pain Centralization. Ann Rheum Dis. 2015; 74(Suppl 2): 313.

Uploaded: Jun 11, 2015
Type: Pdf
TNX-102 SL* for Treatment of Fibromyalgia: Approaches to Pain Measurement

TNX-102 SL* for Treatment of Fibromyalgia: Approaches to Pain Measurement

Poster Presentation at the European Union League Against Rheumatism (EULAR) 2015 Annual Meeting in Rome, IT

Gendreau RM, Clauw D, Gendreau JF, Daugherty BL, Lederman S. THU0322 TNX-102 SL for Treatment of Fibromyalgia: Approaches to Pain Measurement. Ann Rheum Dis. 2015; 74(Suppl 2): 312.

Uploaded: Jun 11, 2015
Type: Pdf
Serotonin Receptor Profiles of Bedtime Pharmacotherapies Targeting Posttraumatic Stress Disorder (PTSD)

Serotonin Receptor Profiles of Bedtime Pharmacotherapies Targeting Posttraumatic Stress Disorder (PTSD)

Poster Presentation at the Society of Biological Psychiatry 2015 Annual Meeting in Toronto, CA

Daugherty B, Sullivan G, Gershell L, Lederman S. 728. Serotonin Receptor Profiles of Bedtime Pharmacotherapies Targeting Posttraumatic Stress Disorder (PTSD). Biological Psychiatry. 2015; 77(Suppl 1): 271S-272S.

Uploaded: May 19, 2015
Type: Pdf
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